Increased Periodontal Attachment Loss in Patients With Systemic Sclerosis

Letter to the Editor: Re: Increased Periodontal Attachment Loss in Patients With Systemic Sclerosis.

BACKGROUND Patients with inflammatory rheumatic diseases and periodontitis share common pathogenetic characteristics, such as proinflammatory traits causative for tissue degradation and loss of function. The aim of the present case control study is to investigate the association between systemic sclerosis (SSc) and periodontitis. METHODS The association between SSc and periodontitis was exami...

Increased Serum Levels of Soluble B7-H4 in Patients with Systemic Lupus Erythematosus

Increased Expression of miR-202-3p in Patients with Relapsing-Remitting Multiple Sclerosis

Background and objectives: One of the latest studies in the genetics field is the evaluation of role of micro-RNAs as a biomarker for diagnosis of multiple sclerosis (MS), which is a demyelinating disease of the central nervous system (CNS) and emerges in the form of numerous small and large plaques in white matter in the brain and spinal cord. This disease could be associated with several comp...

Increased IL-17A but Decreased IL-27 Serum Levels in Patients with Multiple Sclerosis

Background: Effector CD4+ T cell subsets play an important role in Multiple Sclerosis (MS). Interleukin-27 (IL-27) suppresses Th (Th1, Th2 and Th17) cells and dampens autoimmunity and tissue inflammation by promoting the generation of Type 1 regulatory T cells (Tr1). Objective: To identify the relative levels of IL-27 and IL-17A in MS disease. Method: In a case-control study, venous blood was c...

Tooth loss in periodontal patients.

OBJECTIVE To compare tooth loss between patients who received surgical therapy for chronic periodontitis and those who received nonsurgical therapy alone. METHODS A retrospective chart study was conducted at Dalhousie University. All patients who had periodontal treatment and were active cases for at least 10 years were included (n = 335). The sample consisted of 120 males (35.8%) and 215 fem...